Noninvasive liver fibrosis evaluation and monitoring during antiviral treatment would be very useful in clinical practice. For that purpose some easily calculated indices are used. APRI and FIB-4 indices are calculated using AST blood activity and platelets count. According to obtained data both indices are suitable for the evaluation of severe fibrosis in patients with chronic hepatitis C.

Keywords: hepatitis C, fibrosis, non-invasive markers of fibrosis, indices